Inhalation of hydrogen gas elevates urinary 8-hydroxy-2′-deoxyguanine in Parkinson's disease
Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson's disease.
Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.
Pilot study of H₂ therapy in Parkinson's disease: a randomized double-blind placebo-controlled trial.
Hydrogen gas inhibits lung cancer progression through targeting SMC3
Molecular hydrogen suppresses glioblastoma growth via inducing the glioma stem-like cell differentiation.
Molecular hydrogen decelerates rheumatoid arthritis progression through inhibition of oxidative stress
Stroke-Induced Brain Injury
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Stroke-Induced Liver Injury
Inhalation of hydrogen gas suppresses hepatic injury caused by ischemia/reperfusion through reducing oxidative stress.
Metabolic Syndrome (diabetes, high cholesterol, obesity, high blood pressure)
Effectiveness of Hydrogen Rich Water on Antioxidant Status of Subjects with Potential Metabolic Syndrome—An Open Label Pilot Study.
Sepsis (bacterial infection)
Protective effects of hydrogen gas on murine polymicrobial sepsis via reducing oxidative stress and HMGB1 release.
Hydrogen Gas Alleviates the Intestinal Injury Caused by Severe Sepsis in Mice by Increasing the Expression of Heme Oxygenase-1
The Effects of Hydrogen Gas Inhalation on Adverse Left Ventricular Remodeling After Percutaneous Coronary Intervention for ST-Elevated Myocardial Infarction - First Pilot Study in Humans.
Hydrogen inhalation during normoxic resuscitation improves neurological outcome in a rat model of cardiac arrest independently of targeted temperature management.
Feasibility and Safety of Hydrogen Gas Inhalation for Post-Cardiac Arrest Syndrome - First-in-Human Pilot Study.
Inhalation of Hydrogen Gas Is Beneficial for Preventing Contrast-Induced Acute Kidney Injury in Rats.
Hydrogen gas alleviates chronic intermittent hypoxia-induced renal injury through reducing iron overload.
Hydrogen gas inhalation inhibits progression to the "irreversible" stage of shock after severe hemorrhage in rats.
Pilot study: Effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes.
Hydrogen water drinking exerts antifatigue effects in chronic forced swimming mice via antioxidative and anti-inflammatory activities.
The role of the reactive oxygen species and oxidative stress in the pathomechanism of the age-related ocular diseases and other pathologies of the anterior and posterior eye segments in adults.
Inhalation of hydrogen gas attenuates airway inflammation and oxidative stress in allergic asthmatic mice.
Recent progress toward hydrogen medicine: potential of molecular hydrogen for preventive and therapeutic applications.
The evolution of molecular hydrogen: a noteworthy potential therapy with clinical significance.
Hydrogen Gas in Cancer Treatment.